Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection

Type I IFNs promote cellular responses to viruses, and IFN receptor (IFNAR) signaling regulates the responses of endothelial cells of the blood-brain barrier (BBB) during neurotropic viral infection. However, the role of astrocytes in innate immune responses of the BBB during viral infection of the...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Daniels, Brian P., Jujjavarapu, Harsha, Durrant, Douglas M., Williams, Jessica L., Green, Richard R., White, James P., Lazear, Helen M., Gale, Michael, Diamond, Michael S., Klein, Robyn S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330728/
https://ncbi.nlm.nih.gov/pubmed/28134626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88720
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