Legomedicine—A Versatile Chemo-Enzymatic Approach for the Preparation of Targeted Dual-Labeled Llama Antibody–Nanoparticle Conjugates

[Image: see text] Conjugation of llama single domain antibody fragments (Variable Heavy chain domains of Heavy chain antibodies, VHHs) to diagnostic or therapeutic nanoparticles, peptides, proteins, or drugs offers many opportunities for optimized targeted cancer treatment. Currently, mostly nonspec...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: van Lith, Sanne A. M., van Duijnhoven, Sander M. J., Navis, Anna C., Leenders, William P. J., Dolk, Edward, Wennink, Jos W. H., van Nostrum, Cornelus F., van Hest, Jan C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330650/
https://ncbi.nlm.nih.gov/pubmed/28045502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00638
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