Histologic transformation of EGFR mutant lung adenocarcinoma without exposure to EGFR inhibition

Resistance to EGFR kinase inhibitors appears to be invariable in the treatment of non-small cell lung cancer. Several mechanisms have been described. Here, we report the first case of histologic transformation of EGFR mutant lung adenocarcinoma without prior exposure to EGFR inhibition.

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Bibliografische gegevens
Gepubliceerd in:Lung Cancer
Hoofdauteurs: Le, Tri, Sailors, Joseph, Oliver, Dwight H., Mayer, Melissa, Hoskin, Sharon, Gerber, David E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330183/
https://ncbi.nlm.nih.gov/pubmed/28236979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2017.01.005
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