Human amnion epithelial cells rescue cell death via immunomodulation of microglia in a mouse model of perinatal brain injury

BACKGROUND: Human amnion epithelial cells (hAECs) are clonogenic and have been proposed to reduce inflammatory-induced tissue injury. Perturbation of the immune response is implicated in the pathogenesis of perinatal brain injury; modulating this response could thus be a novel therapy for treating o...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Leaw, Bryan, Zhu, Dandan, Tan, Jean, Muljadi, Ruth, Saad, Mohamed I., Mockler, Joanne C., Wallace, Euan M., Lim, Rebecca, Tolcos, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330154/
https://ncbi.nlm.nih.gov/pubmed/28241859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0496-3
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