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Insights on chiral, backbone modified peptide nucleic acids: Properties and biological activity
PNAs are emerging as useful synthetic devices targeting natural miRNAs. In particular 3 classes of structurally modified PNAs analogs are herein described, namely α, β and γ, which differ by their backbone modification. Their mode and binding affinity for natural nucleic acids and their use in medic...
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| Udgivet i: | Artif DNA PNA XNA |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5329900/ https://ncbi.nlm.nih.gov/pubmed/26752710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/1949095X.2015.1107176 |
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