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Sex and the Circuitry: Progress Toward a Systems-Level Understanding of Vertebrate Sex Determination
In vertebrates, the gonad arises as a bipotential primordium that can differentiate as a testis or ovary. Cells are initially primed to adopt either fate by balanced antagonistic signaling pathways and transcription networks. Sexual fate is determined by activating the testis or ovarian pathway and...
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| Publicado no: | Wiley Interdiscip Rev Syst Biol Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5329888/ https://ncbi.nlm.nih.gov/pubmed/22605638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1172 |
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