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Retroviral integrase protein and intasome nucleoprotein complex structures

Retroviral replication proceeds through the integration of a DNA copy of the viral RNA genome into the host cellular genome, a process that is mediated by the viral integrase (IN) protein. IN catalyzes two distinct chemical reactions: 3’-processing, whereby the viral DNA is recessed by a di- or trin...

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Bibliografiske detaljer
Udgivet i:World J Biol Chem
Main Authors: Grawenhoff, Julia, Engelman, Alan N
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329712/
https://ncbi.nlm.nih.gov/pubmed/28289517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v8.i1.32
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