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Impact of T cells on hematopoietic stem and progenitor cell function: Good guys or bad guys?

When hematopoietic stem and progenitor cells (HSPC) are harvested for transplantation, either from the bone marrow or from mobilized blood, the graft contains a significant number of T cells. It is these T cells that are the major drivers of graft-vs-host disease (GvHD). The risk for GvHD can simply...

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Detalhes bibliográficos
Publicado no:World J Stem Cells
Main Authors: Geerman, Sulima, Nolte, Martijn A
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329688/
https://ncbi.nlm.nih.gov/pubmed/28289507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4252/wjsc.v9.i2.37
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