Extracellular Acidification Inhibits the ROS-Dependent Formation of Neutrophil Extracellular Traps

The inflammatory microenvironment is commonly characterized by extracellular acidosis (pH < 7.35). Sensitivity to pH, CO(2) or bicarbonate concentrations allows neutrophils to react to changes in their environment and to detect inflamed areas in the tissue. One important antimicrobial effector me...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Behnen, Martina, Möller, Sonja, Brozek, Antonia, Klinger, Matthias, Laskay, Tamás
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329032/
https://ncbi.nlm.nih.gov/pubmed/28293240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00184
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