Tumor trapping of 5-fluorouracil: in vivo 19F NMR spectroscopic pharmacokinetics in tumor-bearing humans and rabbits.

The pharmacokinetics of 5-fluorouracil (5FU) were studied in vivo in patients with discrete tumors and in rabbits bearing VX2 tumors by using 19F NMR spectroscopy. The human studies were conducted in a 1.5-T Magnetom magnetic resonance imager (Siemens), and the rabbit studies were conducted in a 4.7...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Wolf, W, Presant, C A, Servis, K L, el-Tahtawy, A, Albright, M J, Barker, P B, Ring, R, Atkinson, D, Ong, R, King, M
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1990
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53290/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.492
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