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Interferon Lambda: Modulating Immunity in Infectious Diseases
Interferon lambdas (IFN-λs; IFNL1-4) modulate immunity in the context of infections and autoimmune diseases, through a network of induced genes. IFN-λs act by binding to the heterodimeric IFN-λ receptor (IFNLR), activating a STAT phosphorylation-dependent signaling cascade. Thereby hundreds of IFN-s...
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| Publié dans: | Front Immunol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328987/ https://ncbi.nlm.nih.gov/pubmed/28293236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00119 |
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