Relation of spontaneous transformation in cell culture to adaptive growth and clonal heterogeneity.

Cell transformation in culture is marked by the appearance of morphologically altered cells that continue to multiply to form discrete foci in confluent sheets when the surrounding cells are inhibited. These foci occur spontaneously in early-passage NIH 3T3 cells grown to confluency in 10% calf seru...

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Bibliographic Details
Main Authors: Rubin, A L, Yao, A, Rubin, H
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53288/
https://ncbi.nlm.nih.gov/pubmed/2296603
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