Estimating the effect of endogenous dopamine on baseline [(11)C]-(+)-PHNO binding in the human brain

Endogenous dopamine (DA) levels at dopamine D(2/3) receptors (D(2/3)R) have been quantified in the living human brain using the agonist radiotracer [(11)C]-(+)-PHNO. As an agonist radiotracer, [(11)C]-(+)-PHNO is more sensitive to endogenous DA levels than antagonist radiotracers. We sought to deter...

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Gepubliceerd in:Synapse
Hoofdauteurs: Caravaggio, Fernando, Kegeles, Lawrence S., Wilson, Alan A., Remington, Gary, Borlido, Carol, Mamo, David C., Graff-Guerrero, Ariel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328677/
https://ncbi.nlm.nih.gov/pubmed/27341789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21920
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