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CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa
Recessive dystrophic epidermolysis bullosa (RDEB) is a severe disorder caused by mutations to the COL7A1 gene that deactivate production of a structural protein essential for skin integrity. Haematopoietic cell transplantation can ameliorate some of the symptoms; however, significant side effects fr...
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| Publicado no: | NPJ Regen Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328670/ https://ncbi.nlm.nih.gov/pubmed/28250968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjregenmed.2016.14 |
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