Enhancing the oral bioavailability of biochanin A by encapsulation in mixed micelles containing Pluronic F127 and Plasdone S630

Biochanin A (BCA), a natural dietary isoflavone, has been reported to show anticancer activities. However, its low biological availability and poor aqueous solubility limit its usefulness as a chemotherapeutic agent. We developed BCA-loaded micelles with Pluronic F127 and Plasdone S630 (BCA-FS). The...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Wu, Xiaoyan, Ge, Weihong, Shao, Tengfei, Wu, Weijun, Hou, Jian, Cui, Li, Wang, Jing, Zhang, Zhenghai
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328660/
https://ncbi.nlm.nih.gov/pubmed/28260893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S125041
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