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Calcineurin, the Ca(2+)-dependent phosphatase, regulates Rga2, a Cdc42 GTPase-activating protein, to modulate pheromone signaling

Calcineurin, the conserved Ca(2+)/calmodulin-activated phosphatase, is required for viability during prolonged exposure to pheromone and acts through multiple substrates to down-regulate yeast pheromone signaling. Calcineurin regulates Dig2 and Rod1/Art4 to inhibit mating-induced gene expression and...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Ly, Nina, Cyert, Martha S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328617/
https://ncbi.nlm.nih.gov/pubmed/28077617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0432
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