A Multistrain Mathematical Model To Investigate the Role of Pyrazinamide in the Emergence of Extensively Drug-Resistant Tuberculosis

Several infectious diseases of global importance—e.g., HIV infection and tuberculosis (TB)—require prolonged treatment with combination antimicrobial regimens typically involving high-potency core agents coupled with additional companion drugs that protect against the de novo emergence of mutations...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Fofana, Mariam O., Shrestha, Sourya, Knight, Gwenan M., Cohen, Ted, White, Richard G., Cobelens, Frank, Dowdy, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Epidemiology and Surveillance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328532/
https://ncbi.nlm.nih.gov/pubmed/27956422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00498-16
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