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Real-Time Monitoring of nfxB Mutant Occurrence and Dynamics in Pseudomonas aeruginosa Biofilm Exposed to Subinhibitory Concentrations of Ciprofloxacin

Biofilm infections caused by Pseudomonas aeruginosa are frequently treated with ciprofloxacin (CIP); however, resistance rapidly develops. One of the primary resistance mechanisms is the overexpression of the MexCD-OprJ pump due to a mutation in nfxB, encoding the transcriptional repressor of this p...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Zaborskyte, Greta, Andersen, Jens Bo, Kragh, Kasper Nørskov, Ciofu, Oana
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328521/
https://ncbi.nlm.nih.gov/pubmed/27993856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02292-16
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