In Vitro Activity of Gepotidacin (GSK2140944) against Neisseria gonorrhoeae

Gepotidacin (formerly GSK2140944) is a novel, first-in-class, triazaacenaphthylene antibacterial that inhibits bacterial DNA gyrase and topoisomerase IV via a unique mechanism and has demonstrated in vitro activity against Neisseria gonorrhoeae, including drug-resistant strains, and also targets pat...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Farrell, D. J., Sader, H. S., Rhomberg, P. R., Scangarella-Oman, N. E., Flamm, R. K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328517/
https://ncbi.nlm.nih.gov/pubmed/28069643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02047-16
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