PER-8, a Novel Extended-Spectrum β-Lactamase PER Variant, from an Acinetobacter baumannii Clinical Isolate in Nepal

A novel PER-type extended-spectrum β-lactamase, PER-8, was identified in an Acinetobacter baumannii clinical isolate obtained in Nepal. The amino acid sequence of PER-8 has a substitution at position 39 (Gly to Glu) compared with that of PER-7. The k(cat)/K(m) ratio of PER-8 for aztreonam was lower...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Tada, Tatsuya, Shrestha, Shovita, Shimada, Kayo, Ohara, Hiroshi, Sherchand, Jeevan B., Pokhrel, Bharat M., Kirikae, Teruo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328513/
https://ncbi.nlm.nih.gov/pubmed/28031203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02300-16
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