Anaplasma marginale Outer Membrane Protein A Is an Adhesin That Recognizes Sialylated and Fucosylated Glycans and Functionally Depends on an Essential Binding Domain

Anaplasma marginale causes bovine anaplasmosis, a debilitating and potentially fatal tick-borne infection of cattle. Because A. marginale is an obligate intracellular organism, its adhesins that mediate entry into host cells are essential for survival. Here, we demonstrate that A. marginale outer me...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Hebert, Kathryn S., Seidman, David, Oki, Aminat T., Izac, Jerilyn, Emani, Sarvani, Oliver, Lee D., Miller, Daniel P., Tegels, Brittney K., Kannagi, Reiji, Marconi, Richard T., Carlyon, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328490/
https://ncbi.nlm.nih.gov/pubmed/27993973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00968-16
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