Copper Is a Host Effector Mobilized to Urine during Urinary Tract Infection To Impair Bacterial Colonization

Urinary tract infection (UTI) is a major global infectious disease affecting millions of people annually. Human urinary copper (Cu) content is elevated during UTI caused by uropathogenic Escherichia coli (UPEC). UPEC upregulates the expression of Cu efflux genes during clinical UTI in patients as an...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Hyre, Amanda N., Kavanagh, Kylie, Kock, Nancy D., Donati, George L., Subashchandrabose, Sargurunathan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328488/
https://ncbi.nlm.nih.gov/pubmed/28031261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01041-16
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