Association between TP53 gene Arg72Pro polymorphism and Wilms’ tumor risk in a Chinese population

Wilms’ tumor is one of the most prevalent pediatric malignancies, ranking fourth in childhood cancer worldwide. TP53 is a critical tumor suppressor gene, which encodes a 53 kDa protein, p53. The p53 functions to protect against cancer by regulating cell cycle and apoptosis and maintaining DNA integr...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Fu, Wen, Zhuo, Zhen-Jian, Jia, Wei, Zhu, Jinhong, Zhu, Shi-Bo, Lin, Ze-Feng, Wang, Feng-Hua, Xia, Huimin, He, Jing, Liu, Guo-Chang
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328300/
https://ncbi.nlm.nih.gov/pubmed/28260929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S131014
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