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Repeated dexamphetamine treatment alters the dopaminergic system and increases the phMRI response to methylphenidate

Dexamphetamine (AMPH) is a psychostimulant drug that is used both recreationally and as medication for attention deficit hyperactivity disorder. Preclinical studies have demonstrated that repeated exposure to AMPH can induce damage to nerve terminals of dopamine (DA) neurons. We here assessed the un...

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Veröffentlicht in:PLoS One
Hauptverfasser: Schrantee, Anouk, Tremoleda, Jordi L., Wylezinska-Arridge, Marzena, Bouet, Valentine, Hesseling, Peter, Meerhoff, Gideon F., de Bruin, Kora M., Koeleman, Jan, Freret, Thomas, Boulouard, Michel, Desfosses, Emilie, Galineau, Laurent, Gozzi, Alessandro, Dauphin, François, Gsell, Willy, Booij, Jan, Lucassen, Paul J., Reneman, Liesbeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328278/
https://ncbi.nlm.nih.gov/pubmed/28241065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172776
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