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HPV 16 E5 oncoprotein is expressed in early stage carcinogenesis and can be a target of immunotherapy

HPV16 persistent infection is a well-known condition that precedes human cancer development. High risk HPV E5 proteins cooperate with E6/E7 oncogenes to promote hyper-proliferation of infected cells leading to possible cancer progression. Thus, presence of E5 viral transcripts could be a key marker...

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Détails bibliographiques
Publié dans:Hum Vaccin Immunother
Auteurs principaux: Paolini, Francesca, Curzio, Gianfranca, Cordeiro, Marcelo Nazario, Massa, Silvia, Mariani, Luciano, Pimpinelli, Fulvia, de Freitas, Antonio Carlos, Franconi, Rosella, Venuti, Aldo
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328231/
https://ncbi.nlm.nih.gov/pubmed/27929754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1264777
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