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Vascular Function and Uric Acid-Lowering in Stage 3 CKD

Hyperuricemia may contribute to endothelial dysfunction in CKD. We evaluated whether lowering serum uric acid levels with allopurinol improves endothelial dysfunction in 80 participants ≥18 years of age with stage 3 CKD and asymptomatic hyperuricemia (≥7 mg/dl in men and ≥6 mg/dl in women) randomize...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Jalal, Diana I., Decker, Emily, Perrenoud, Loni, Nowak, Kristen L., Bispham, Nina, Mehta, Tapan, Smits, Gerard, You, Zhiying, Seals, Douglas, Chonchol, Michel, Johnson, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328166/
https://ncbi.nlm.nih.gov/pubmed/27620990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016050521
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