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Expression of human adenosine deaminase in mice reconstituted with retrovirus-transduced hematopoietic stem cells.

Recombinant retroviruses encoding human adenosine deaminase (ADA; adenosine aminohydrolase, EC 3.5.4.4) have been used to infect murine hematopoietic stem cells. In bone marrow transplant recipients reconstituted with the genetically modified cells, human ADA was detected in peripheral blood mononuc...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Wilson, J M, Danos, O, Grossman, M, Raulet, D H, Mulligan, R C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296599/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.439
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