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Primary Double-Strike Therapy for Cancers to Overcome EGFR Kinase Inhibitor Resistance: Proposal from the Bench

Diverse molecular mechanisms that confer acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) in lung cancers with sensitive EGFR mutations have been reported. However, it is not realistic to analyze for all these mechanisms at the time of resistance in clinical practice and establish adequ...

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Bibliographic Details
Published in:J Thorac Oncol
Main Authors: Suda, Kenichi, Bunn, Paul A., Rivard, Christopher J., Mitsudomi, Tetsuya, Hirsch, Fred R.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327855/
https://ncbi.nlm.nih.gov/pubmed/27642065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2016.09.003
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