Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity

The transmembrane four L6 family member 5 (TM4SF5) protein is a novel molecular target for the prevention and treatment of hepatocellular carcinoma. TM4SF5 is highly expressed in liver, colon, esophageal, and pancreatic cancers and is implicated in tumor progression. Here, we screened monoclonal ant...

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Enregistré dans:
Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Ahn, Hye-Mi, Ryu, Jihye, Song, Jin Myeong, Lee, Yunhee, Kim, Hye-Jin, Ko, Dongjoon, Choi, Inpyo, Kim, Sang Jick, Lee, Jung Weon, Kim, Semi
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327636/
https://ncbi.nlm.nih.gov/pubmed/28255353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.15629
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