Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy

Seizure-driven brain damage in epilepsy accumulates over time, especially in the hippocampus, which can lead to sclerosis, cognitive decline, and death. Excitotoxicity is the prevalent model to explain ictal neurodegeneration. Current labeling technologies cannot distinguish between excitotoxicity a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leal-Campanario, Rocio, Alarcon-Martinez, Luis, Rieiro, Hector, Martinez-Conde, Susana, Alarcon-Martinez, Tugba, Zhao, Xiuli, LaMee, Jonathan, Popp, Pamela J. Osborn, Calhoun, Michael E., Arribas, Juan I., Schlegel, Alexander A., Stasi, Leandro L. Di, Rho, Jong M., Inge, Landon, Otero-Millan, Jorge, Treiman, David M., Macknik, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327474/
https://ncbi.nlm.nih.gov/pubmed/28240297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43276
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