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Nonsteroidal anti-inflammatory drugs modulate cellular glycosaminoglycan synthesis by affecting EGFR and PI3K signaling pathways

In this report, selected non-steroidal anti-inflammatory drugs (NSAIDs), indomethacin and nimesulide, and analgesics acetaminophen, alone, as well as in combination with isoflavone genistein as potential glycosaminoglycan (GAG) metabolism modulators were considered for the treatment of mucopolysacch...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mozolewski, Paweł, Moskot, Marta, Jakóbkiewicz-Banecka, Joanna, Węgrzyn, Grzegorz, Bocheńska, Katarzyna, Banecki, Bogdan, Gabig-Cimińska, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327420/
https://ncbi.nlm.nih.gov/pubmed/28240227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43154
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