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Mechanisms of Immune Suppression Utilized by Canine Adipose and Bone Marrow-Derived Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) from rodents and humans have been shown to suppress T cells by distinct primary pathways, with nitric oxide (NO)-dependent pathways dominating in rodents and indoleamine 2,3-deoxygenase (IDO)-dependent pathways dominating in humans. However, the immune suppressive pathw...

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Bibliographic Details
Published in:Stem Cells Dev
Main Authors: Chow, Lyndah, Johnson, Valerie, Coy, Jonathan, Regan, Dan, Dow, Steven
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327053/
https://ncbi.nlm.nih.gov/pubmed/27881051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0207
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