Degenerative myelopathy in the Collie breed: a retrospective immunohistochemical analysis of superoxide dismutase 1 in an affected Rough Collie, and a molecular epidemiological survey of the SOD1: c.118G>A mutation in Japan

Canine degenerative myelopathy (DM) is an adult-onset, progressive neurodegenerative disease that occurs in multiple dog breeds. A DM-associated mutation of the canine superoxide dismutase 1 (SOD1) gene, designated as c.118G>A (p.E40K), has been implicated as one of pathogenetic determinants of t...

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Dettagli Bibliografici
Pubblicato in:J Vet Med Sci
Autori principali: KOHYAMA, Moeko, KITAGAWA, Masato, KAMISHINA, Hiroaki, KOBATAKE, Yui, YABUKI, Akira, SAWA, Mariko, KAKITA, Shusaku, YAMATO, Osamu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Japanese Society of Veterinary Science 2016
Soggetti:
Clinical Pathology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326944/
https://ncbi.nlm.nih.gov/pubmed/27941298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.16-0391
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