HLA-B(*)57 Allele Is Associated with Concomitant Anti-tuberculosis and Antiretroviral Drugs Induced Liver Toxicity in Ethiopians

Drug-induced liver injury (DILI) is a known adverse effect of both anti-tuberculosis (anti-TB) and antiretroviral (ARV) drugs. Recent studies highlight the implications of genetic predispositions to DILI. We performed a case-control study to identify Human Leukocyte Antigen-B (HLA-B) variant alleles...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Petros, Zelalem, Kishikawa, Junko, Makonnen, Eyasu, Yimer, Getnet, Habtewold, Abiy, Aklillu, Eleni
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326775/
https://ncbi.nlm.nih.gov/pubmed/28289388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00090
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