Preadolescent adversity programs a disrupted maternal stress reactivity in humans and mice

BACKGROUND: Adverse childhood experiences (ACEs) are one of the greatest predictors for affective disorders for women. Periods of dynamic hormonal flux, including pregnancy, exacerbate the risk for affective disturbance and promote hypothalamic-pituitary-adrenal (HPA) axis dysregulation, a key featu...

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Pubblicato in:Biol Psychiatry
Autori principali: Morrison, Kathleen E., Epperson, C. Neill, Sammel, Mary D., Ewing, Grace, Podcasy, Jessica S., Hantsoo, Liisa, Kim, Deborah R., Bale, Tracy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326692/
https://ncbi.nlm.nih.gov/pubmed/27776734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.08.027
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