BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes

Allele-specific measurements of transcription factor binding from ChIP-seq data are key to dissecting the allelic effects of non-coding variants and their contribution to phenotypic diversity. However, most methods of detecting an allelic imbalance assume diploid genomes. This assumption severely li...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: de Santiago, Ines, Liu, Wei, Yuan, Ke, O’Reilly, Martin, Chilamakuri, Chandra Sekhar Reddy, Ponder, Bruce A. J., Meyer, Kerstin B., Markowetz, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326502/
https://ncbi.nlm.nih.gov/pubmed/28235418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1165-7
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