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H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer

Epigenetics, the modification of chromatin without changing the DNA sequence itself, determines whether a gene is expressed, and how much of a gene is expressed. Methylation of lysine 27 on histone 3 (H3K27me), a modification usually associated with gene repression, has established roles in regulati...

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Detalhes bibliográficos
Publicado no:Adv Cancer Res
Main Authors: Nichol, Jessica N., Dupéré-Richer, Daphné, Ezponda, Teresa, Licht, Jonathan D., Miller, Wilson H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325795/
https://ncbi.nlm.nih.gov/pubmed/27451124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2016.05.001
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