Pseudogenization of the secreted effector gene sseI confers rapid systemic dissemination of S. Typhimurium ST313 within migratory dendritic cells

Genome degradation correlates with host adaptation and systemic disease in Salmonella. Most lineages of the S. enterica subspecies Typhimurium cause gastroenteritis in humans, however, the recently emerged ST313 lineage II pathovar commonly causes systemic bacteremia in sub-Saharan Africa. ST313 lin...

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Publicado en:Cell Host Microbe
Autores principales: Carden, Sarah E., Walker, Gregory T., Honeycutt, Jared, Lugo, Kyler, Pham, Trung, Jacobson, Amanda, Bouley, Donna, Idoyaga, Juliana, Tsolis, Renee M., Monack, Denise
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325708/
https://ncbi.nlm.nih.gov/pubmed/28182950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.01.009
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