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Hippocampal activation is associated with longitudinal amyloid accumulation and cognitive decline

The amyloid hypothesis suggests that beta-amyloid (Aβ) deposition leads to alterations in neural function and ultimately to cognitive decline in Alzheimer’s disease. However, factors that underlie Aβ deposition are incompletely understood. One proposed model suggests that synaptic activity leads to...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Leal, Stephanie L, Landau, Susan M, Bell, Rachel K, Jagust, William J
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325620/
https://ncbi.nlm.nih.gov/pubmed/28177283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22978
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