Functional diversity of secreted cestode Kunitz proteins: Inhibition of serine peptidases and blockade of cation channels

We previously reported a multigene family of monodomain Kunitz proteins from Echinococcus granulosus (EgKU-1-EgKU-8), and provided evidence that some EgKUs are secreted by larval worms to the host interface. In addition, functional studies and homology modeling suggested that, similar to monodomain...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Fló, Martín, Margenat, Mariana, Pellizza, Leonardo, Graña, Martín, Durán, Rosario, Báez, Adriana, Salceda, Emilio, Soto, Enrique, Alvarez, Beatriz, Fernández, Cecilia
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325619/
https://ncbi.nlm.nih.gov/pubmed/28192542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006169
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