Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes

Picornaviruses are non-enveloped RNA viruses that enter cells via receptor-mediated endocytosis. Because they lack an envelope, picornaviruses face the challenge of delivering their RNA genomes across the membrane of the endocytic vesicle into the cytoplasm to initiate infection. Currently, the mech...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Groppelli, Elisabetta, Levy, Hazel C., Sun, Eileen, Strauss, Mike, Nicol, Clare, Gold, Sarah, Zhuang, Xiaowei, Tuthill, Tobias J., Hogle, James M., Rowlands, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325612/
https://ncbi.nlm.nih.gov/pubmed/28166307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006197
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