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Phase modulation of insulin pulses enhances glucose regulation and enables inter-islet synchronization

Insulin is secreted in a pulsatile manner from multiple micro-organs called the islets of Langerhans. The amplitude and phase (shape) of insulin secretion are modulated by numerous factors including glucose. The role of phase modulation in glucose homeostasis is not well understood compared to the o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Boah, Song, Taegeun, Lee, Kayoung, Kim, Jaeyoon, Han, Seungmin, Berggren, Per-Olof, Ryu, Sung Ho, Jo, Junghyo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325581/
https://ncbi.nlm.nih.gov/pubmed/28235104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172901
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