Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies

Myeloid-derived suppressor cells (MDSCs) play a pivotal role in promoting tumor growth and metastasis and can even decrease the efficacy of immunotherapy. In breast cancer, MDSCs are recruited mainly by breast cancer cells to form a tumor-favoring microenvironment to suppress the anti-tumor immune r...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Shou, Dawei, Wen, Liang, Song, Zhenya, Yin, Jian, Sun, Qiming, Gong, Weihua
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325458/
https://ncbi.nlm.nih.gov/pubmed/27542274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11352
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