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Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1)

The process of tumor invasion requires degradation of extracellular matrix by proteolytic enzymes. Cancer cells form protrusive invadopodia, which produce and release matrix metalloproteinases (MMPs) to degrade the basement membrane thereby enabling metastasis. We investigated the effect of LASP1, a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Endres, Marcel, Kneitz, Susanne, Orth, Martin F., Perera, Ruwan K., Zernecke, Alma, Butt, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325439/
https://ncbi.nlm.nih.gov/pubmed/27588391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11720
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