AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts

Valosin containing protein (p97) is a chaperone implicated in a large number of biological processes including endoplasmic reticulum (ER)-associated protein degradation and autophagy. Silencing of p97 in rheumatoid arthritis (RA) synovial fibroblasts (RASFs) increased the amount of polyubiquitinated...

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Udgivet i:Oncotarget
Main Authors: Kato, Masaru, Ospelt, Caroline, Kolling, Christoph, Shimizu, Tomohiro, Kono, Michihito, Yasuda, Shinsuke, Michel, Beat A., Gay, Renate E., Gay, Steffen, Klein, Kerstin, Atsumi, Tatsuya
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325437/
https://ncbi.nlm.nih.gov/pubmed/27623077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11890
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