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Transcriptomic and functional pathways analysis of ascorbate-induced cytotoxicity and resistance of Burkitt lymphoma

Ascorbate is a pro-oxidant that generates hydrogen peroxide–dependent cytotoxity in cancer cells without adversely affecting normal cells. To determine the mechanistic basis for this phenotype, we selected Burkitt lymphoma cells resistant to ascorbate (JLPR cells) and their ascorbate-sensitive paren...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pei, Zenglin, Zhang, Xuan, Ji, Chunxia, Liu, Song-Mei, Wang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325416/
https://ncbi.nlm.nih.gov/pubmed/27590508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11740
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