Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2

Resistance of bladder cancer to cisplatin is a major obstacle to successful treatment. In the current study, we investigated the apoptotic effects of curcumin and cisplatin co-treatment in 253J-Bv(p53 wild-type) and T24(p53 mutant) bladder cancer. We found that curcumin and cisplatin co-treatment pr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Bong Hee, Lim, Joung Eun, Jeon, Hwang Gyun, Il Seo, Seong, Lee, Hyun Moo, Choi, Han Yong, Jeon, Seong Soo, Jeong, Byong Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325410/
https://ncbi.nlm.nih.gov/pubmed/27564099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11563
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