Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and ω6 polyunsaturated fatty acid profiles and deliver immunosuppressive signals to innate immunity cells

Obesity is a low-grade chronic inflammatory state representing an important risk factor for colorectal cancer (CRC). Adipocytes strongly contribute to inflammation by producing inflammatory mediators. In this study we investigated the role of human visceral fat adipocytes in regulating the functions...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Del Cornò, Manuela, D'Archivio, Massimo, Conti, Lucia, Scazzocchio, Beatrice, Varì, Rosaria, Donninelli, Gloria, Varano, Barbara, Giammarioli, Stefania, De Meo, Simone, Silecchia, Gianfranco, Pennestrì, Francesco, Persiani, Roberto, Masella, Roberta, Gessani, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325349/
https://ncbi.nlm.nih.gov/pubmed/27494857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10998
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