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The Ess/Type VII secretion system of Staphylococcus aureus secretes a nuclease toxin that targets competitor bacteria

The type VII protein secretion system (T7SS) plays a critical role in the virulence of human pathogens including Mycobacterium tuberculosis and Staphylococcus aureus. Here we report that the S. aureus T7SS secretes a large nuclease toxin, EsaD. The toxic activity of EsaD is neutralised during its bi...

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Vydáno v:Nat Microbiol
Hlavní autoři: Cao, Zhenping, Casabona, M. Guillermina, Kneuper, Holger, Chalmers, James D., Palmer, Tracy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325307/
https://ncbi.nlm.nih.gov/pubmed/27723728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.183
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