Interleukin-10 reorganizes the cytoskeleton of mature dendritic cells leading to their impaired biophysical properties and motilities

Interlukin-10 (IL-10) is an immunomodulatory cytokine which predominantly induces immune-tolerance. It has been also identified as a major cytokine in the tumor microenvironment that markedly mediates tumor immune escape. Previous studies on the roles of IL-10 in tumor immunosuppression mainly focus...

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Veröffentlicht in:PLoS One
Hauptverfasser: Xu, Xiaoli, Liu, Xianmei, Long, Jinhua, Hu, Zuquan, Zheng, Qinni, Zhang, Chunlin, Li, Long, Wang, Yun, Jia, Yi, Qiu, Wei, Zhou, Jing, Yao, Weijuan, Zeng, Zhu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325303/
https://ncbi.nlm.nih.gov/pubmed/28234961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172523
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